Title : Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity.

Pub. Date : 1993 Feb 15

PMID : 8429040

1 Functional Relationships(s)
Compound Name
Protein Name
1 The rate constants for inhibition of wild-type thrombin by HCII in the presence of heparin or dermatan sulfate were 9.2 x 10(8) M-1 min-1 and 9.0 x 10(8) M-1 min-1, respectively. Dermatan Sulfate serpin family D member 1 Homo sapiens