Title : Effect of pH and denaturants on the folding and stability of murine interleukin-6.

Pub. Date : 1993 Aug

PMID : 8401214






1 Functional Relationships(s)
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1 Replacement of His-33 with Ala-33 in peptide H1 alleviated a significant portion of the pH-dependent quenching of fluorescence suggesting that the interaction of the imidazole ring of His-33 with the indole ring of Trp-36 is a major determinant responsible for the quenching of the endogenous protein fluorescence of mIL-6. imidazole interleukin 6 Mus musculus