Title : Effects of interleukin-1 alpha on arachidonic acid metabolism in human osteosarcoma osteoblastic cells.

Pub. Date : 1993 Jul

PMID : 8395696






2 Functional Relationships(s)
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1 In the G292 cells, IL-1 alpha (50 U/ml) induced a 10-fold increase in PGE2 production at all the incubation times tested, and a significant two-fold increase in 5 hydroxyeicosatetraenoic acid (HETE) formation after 48 h. These effects were not seen in SaOS-2 cells under identical conditions. Hydroxyeicosatetraenoic Acids interleukin 1 alpha Homo sapiens
2 In the G292 cells, IL-1 alpha (50 U/ml) induced a 10-fold increase in PGE2 production at all the incubation times tested, and a significant two-fold increase in 5 hydroxyeicosatetraenoic acid (HETE) formation after 48 h. These effects were not seen in SaOS-2 cells under identical conditions. Hydroxyeicosatetraenoic Acids interleukin 1 alpha Homo sapiens