Title : Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated human platelets.

Pub. Date : 1993 Jun 15

PMID : 8391259






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 On the other hand, tyrphostin treatment of metabolically 32P-labelled platelets significantly inhibited the thrombin-dependent accumulation of PtdIns(3,4)P2, which involves at least a PtdIns 3-kinase and/or a PtdIns3P 4-kinase, whereas the synthesis of phosphatidic acid (PtdOH), a good reflection of the phospholipase C (PLC) activation in platelets, was partially blocked. ptdoh coagulation factor II, thrombin Homo sapiens