Title : Evidence that the major physiological role of TRH in the hypothalamic paraventricular nuclei may be to regulate the set-point for thyroid hormone negative feedback on the pituitary thyrotroph.

Pub. Date : 1993 Apr

PMID : 8367024






1 Functional Relationships(s)
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1 The prompt parallel rate of rise of plasma TSH in Sham and PVN groups following thyroidectomy indicates that a primary physiologic action of TRH in the thyrotroph is to control the set-point for thyroid hormone negative feedback on TSH secretion. Thyrotropin thyrotropin releasing hormone Rattus norvegicus