| Protein Name | thyrotropin releasing hormone |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25569 |
| Gene Symbol | Trh |
| UniProt | P01150 (TRH_RAT), B1WBP2 (B1WBP2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
879
Total Number of Articles : 1486 |
Description |
thyrotropin releasing hormone |
| Gene Summary |
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The rat proprotein contains five thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin, and may be involved in cardiac function in heart failure. Disruption of this gene is associated with hypothyroidism, elevated thyroid-stimulating hormone levels, and hyperglycemia. [provided by RefSeq, May 2013] |
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