Protein Name thyrotropin releasing hormone
Organism Rattus norvegicus
Gene ID 25569
Gene Symbol


UniProt P01150 (TRH_RAT), B1WBP2 (B1WBP2_RAT)
Relationships Total Number of functionally related compound(s) : 879
Total Number of Articles : 1486

thyrotropin releasing hormone

Gene Summary

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The rat proprotein contains five thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin, and may be involved in cardiac function in heart failure. Disruption of this gene is associated with hypothyroidism, elevated thyroid-stimulating hormone levels, and hyperglycemia. [provided by RefSeq, May 2013]

  • thyrotropin releasing hormone
  • TSH-releasing factor
  • pro-thyrotropin-releasing hormone
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