Pub. Date : 1993 Sep
PMID : 8359233
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Posttranscriptional regulation of colony-stimulating factor-1 (CSF-1) and CSF-1 receptor gene expression during inhibition of phorbol-ester-induced monocytic differentiation by dexamethasone and cyclosporin A: potential involvement of a destabilizing protein. | Cyclosporine | colony stimulating factor 1 | Homo sapiens |
2 | The present studies demonstrate that dexamethasone (dex) and cyclosporin A (CsA) resulted in inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced monocytic differentiation of HL60 cells, as well as TPA induction of c-fms and CSF-1 transcripts. | Cyclosporine | colony stimulating factor 1 | Homo sapiens |
3 | The present studies demonstrate that dexamethasone (dex) and cyclosporin A (CsA) resulted in inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced monocytic differentiation of HL60 cells, as well as TPA induction of c-fms and CSF-1 transcripts. | Cyclosporine | colony stimulating factor 1 | Homo sapiens |
4 | Taken together, our results suggest the existence of a labile mRNA regulatory protein or proteins, whose actions include destabilization of both c-fms and CSF-1 transcripts after inhibition of TPA-induced monocytic differentiation by dex or CsA. | Cyclosporine | colony stimulating factor 1 | Homo sapiens |