Protein Name colony stimulating factor 1
Organism Homo sapiens
Gene ID 1435
Gene Symbol

CSF1

UniProt P09603 (CSF1_HUMAN), A0A024R0A1 (A0A024R0A1_HUMAN)
Relationships Total Number of functionally related compound(s) : 447
Total Number of Articles : 648
Description

colony stimulating factor 1

Gene Summary

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

synonyms
  • macrophage colony-stimulating factor 1
  • CSF1-hERV-LTR71B fusion protein
  • colony stimulating factor 1 (macrophage)
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Properties