Pub. Date : 1993 May
PMID : 8358330
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Carnitine palmitoyltransferase I (CPT I), the rate-limiting enzyme for fatty acid oxidation, in platelets obtained from diabetes showed a higher Vmax for palmitoyl-CoA and an increased I50 (concentration giving 50% inhibition of CPT I activity) for malonyl-CoA inhibition. | Fatty Acids | carnitine palmitoyltransferase 1B | Rattus norvegicus |
2 | Carnitine palmitoyltransferase I (CPT I), the rate-limiting enzyme for fatty acid oxidation, in platelets obtained from diabetes showed a higher Vmax for palmitoyl-CoA and an increased I50 (concentration giving 50% inhibition of CPT I activity) for malonyl-CoA inhibition. | Fatty Acids | carnitine palmitoyltransferase 1B | Rattus norvegicus |
3 | From these findings, fatty acid oxidation in platelets, as in the liver, is likely to be regulated by insulin and both increased CPT I activity and decreased sensitivity to malonyl-CoA inhibition are attributable to enhanced platelet fatty acid oxidation in diabetic rats. | Fatty Acids | carnitine palmitoyltransferase 1B | Rattus norvegicus |
4 | From these findings, fatty acid oxidation in platelets, as in the liver, is likely to be regulated by insulin and both increased CPT I activity and decreased sensitivity to malonyl-CoA inhibition are attributable to enhanced platelet fatty acid oxidation in diabetic rats. | Fatty Acids | carnitine palmitoyltransferase 1B | Rattus norvegicus |