Title : Stimulation or inhibition of A431 cell growth by EGF is directly correlated with receptor tyrosine kinase concentration but not with PLC gamma activity.

Pub. Date : 1993

PMID : 8350679






2 Functional Relationships(s)
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1 In the presence of tyrosine kinase inhibitor coumaric acid (0.2 approximately 2 microM), A431 cell growth was stimulated, rather than inhibited, by EGF in a dose-dependent manner. Coumaric Acids epidermal growth factor Homo sapiens
2 Furthermore, in the presence of coumaric acid (up to 0.5 microM), EGF-induced production of inositol phosphates in A431 cells was not obviously affected. Coumaric Acids epidermal growth factor Homo sapiens