Title : Deletion of amino acids Asp487-Ser488-Phe489 in human cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency.

Pub. Date : 1993 Aug

PMID : 8345056






1 Functional Relationships(s)
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1 Analysis of her P450c17 gene by polymerase chain reaction amplification and sequencing showed a nine-base deletion, eliminating codons 487-489 (Asp-Ser-Phe) near the carboxy-terminus of P450c17. Serine cytochrome P450 family 17 subfamily A member 1 Homo sapiens