Title : beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth.

Pub. Date : 1993 Dec

PMID : 8287928






1 Functional Relationships(s)
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1 In this report, we show that beta-amyloid peptide when presented as an insoluble substrate which mimics its conformation in vivo can induce cortical glial cells in vitro and in vivo to locally deposit chondroitin sulfate containing proteoglycan. Chondroitin Sulfates amyloid beta precursor protein Homo sapiens