Title : Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin.

Pub. Date : 1993 Dec 15

PMID : 8280078






2 Functional Relationships(s)
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1 When hepatocytes were incubated with [2-3H, U-14C]glucose, the incorporation of 3H/14C label into glycogen correlated with the extent of glucokinase release. Glycogen glucokinase Homo sapiens
2 Since 2-3H is lost during conversion of glucose 6-phosphate into fructose 6-phosphate, substrate-induced translocation of glucokinase from a Mg(2+)-dependent binding site to an alternative site might favour the partitioning of glucose 6-phosphate towards glycogen, as opposed to phosphoglucoisomerase. Glycogen glucokinase Homo sapiens