Pub. Date : 1994 Jan 7
PMID : 8276819
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Treatment of A-549 human lung adenocarcinoma cells with okadaic acid increased expression of the IGF-II mRNAs. | Okadaic Acid | insulin like growth factor 2 | Homo sapiens |
2 | Since the 4.8-kb mRNA is transcribed under the control of human IGF-II P4 promoter, we examined the P4 promoter element responsible for the okadaic acid-mediated transcriptional activation. | Okadaic Acid | insulin like growth factor 2 | Homo sapiens |
3 | Transfection of IGF-II P4 promoter-chloramphenicol acetyltransferase constructs demonstrated that the effects of okadaic acid on the induction of IGF-II gene expression are mediated through multiple promoter elements, including an Egr-1 consensus element. | Okadaic Acid | insulin like growth factor 2 | Homo sapiens |
4 | Transfection of IGF-II P4 promoter-chloramphenicol acetyltransferase constructs demonstrated that the effects of okadaic acid on the induction of IGF-II gene expression are mediated through multiple promoter elements, including an Egr-1 consensus element. | Okadaic Acid | insulin like growth factor 2 | Homo sapiens |