Title : Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment.

Pub. Date : 1993 Dec

PMID : 8274026






5 Functional Relationships(s)
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1 Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment. Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
2 The present study determined the effect of genetic obesity and phenobarbital (PB) treatment on the expression and regulation of the hepatic cytochrome P450 enzyme (CYP2C11) in Fa/? Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
3 The present study determined the effect of genetic obesity and phenobarbital (PB) treatment on the expression and regulation of the hepatic cytochrome P450 enzyme (CYP2C11) in Fa/? Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
4 Treatment with PB further suppressed hepatic CYP2C11 protein levels and activities in both fa/fa and Fa/? Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
5 The level of CYP2C11 steady-state mRNA was significantly higher after treatment with PB in Fa/? Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus