Title : In vitro metabolism of aflatoxin B1 by normal and tumorous liver tissue from Thailand.

Pub. Date : 1993 Dec

PMID : 8269634






1 Functional Relationships(s)
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1 Microsomal metabolism of AFB1 to AFB1 8,9-epoxide (as measured by AFB1 tris-diol formation) and aflatoxin Q1 (AFQ1), the major metabolite produced, was significantly correlated with CYP3A3/4 expression (P < 0.001) and, to a lesser extent, with CYP2B6 expression (P < 0.01). Aflatoxins cytochrome P450 family 3 subfamily A member 4 Homo sapiens