Title : Insulin stimulates GDP release from G proteins in the rat and human liver plasma membranes.

Pub. Date : 1993 Nov

PMID : 8263034






7 Functional Relationships(s)
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Protein Name
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1 Insulin stimulates GDP release from G proteins in the rat and human liver plasma membranes. Guanosine Diphosphate insulin Homo sapiens
2 In the rat membranes, 1-100 nM glucagon (used as a positive control) stimulated [32P]GDP release by about 17% (P < .05); similarly, 0.1-100 nM insulin stimulated [32P]GDP release by 10-13% (P < .05). Guanosine Diphosphate insulin Homo sapiens
3 In the human membranes, 10 pM to 100 nM insulin stimulated [32P]GDP release by 7-10%. Guanosine Diphosphate insulin Homo sapiens
4 In the rat membranes, 10 nM insulin stimulated [32P]GDP release by 17 and 24% at 2 and 4 min, respectively (P < .05); in the human membranes, 10 nM insulin stimulated [32P]GDP release by about 9% at 2 and 4 min. Guanosine Diphosphate insulin Homo sapiens
5 In the rat membranes, 10 nM insulin stimulated [32P]GDP release by 17 and 24% at 2 and 4 min, respectively (P < .05); in the human membranes, 10 nM insulin stimulated [32P]GDP release by about 9% at 2 and 4 min. Guanosine Diphosphate insulin Homo sapiens
6 In the rat membranes, 10 nM insulin stimulated [32P]GDP release by 17 and 24% at 2 and 4 min, respectively (P < .05); in the human membranes, 10 nM insulin stimulated [32P]GDP release by about 9% at 2 and 4 min. Guanosine Diphosphate insulin Homo sapiens
7 In the rat membranes, 10 nM insulin stimulated [32P]GDP release by 17 and 24% at 2 and 4 min, respectively (P < .05); in the human membranes, 10 nM insulin stimulated [32P]GDP release by about 9% at 2 and 4 min. Guanosine Diphosphate insulin Homo sapiens