Pub. Date : 1994 Mar
PMID : 8206325
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Analysis of the half-life of GnRH mRNA levels after transcriptional arrest with actinomycin-D (5 micrograms/ml) estimated the half-life of GnRH mRNA to be 22 h. TPA treatment did not alter the GnRH mRNA half-life directly, suggesting that the effects of TPA occur predominantly at the level of gene transcription. | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Rattus norvegicus |
| 2 | Analysis of the half-life of GnRH mRNA levels after transcriptional arrest with actinomycin-D (5 micrograms/ml) estimated the half-life of GnRH mRNA to be 22 h. TPA treatment did not alter the GnRH mRNA half-life directly, suggesting that the effects of TPA occur predominantly at the level of gene transcription. | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Rattus norvegicus |
| 3 | Analysis of the half-life of GnRH mRNA levels after transcriptional arrest with actinomycin-D (5 micrograms/ml) estimated the half-life of GnRH mRNA to be 22 h. TPA treatment did not alter the GnRH mRNA half-life directly, suggesting that the effects of TPA occur predominantly at the level of gene transcription. | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Rattus norvegicus |
| 4 | Exposure of cells transiently transfected with various deletion constructs of the rat (r)GnRH promoter to TPA resulted in a decrease of 60% in luciferase reporter activity. | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Rattus norvegicus |