Protein Name gonadotropin releasing hormone 1
Organism Rattus norvegicus
Gene ID 25194
Gene Symbol

Gnrh1

UniProt P07490 (GON1_RAT)
Relationships Total Number of functionally related compound(s) : 1111
Total Number of Articles : 2053
Description

gonadotropin releasing hormone 1

Gene Summary

Enables gonadotropin hormone-releasing hormone activity. Involved in several processes, including estrous cycle; negative regulation of immature T cell proliferation; and response to prolactin. Located in several cellular components, including cytoplasmic side of rough endoplasmic reticulum membrane; cytoplasmic vesicle; and perikaryon. Used to study prostatic hypertrophy. Human ortholog(s) of this gene implicated in breast cancer; hypogonadotropic hypogonadism 12 with or without anosmia; and periodontitis. Orthologous to human GNRH1 (gonadotropin releasing hormone 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • progonadoliberin-1
  • Putative protein SH
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
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Properties