Title : The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins.

Pub. Date : 1994 Jun

PMID : 8183561






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Chimeric Ret and Trk oncoproteins, encoded by different rearrangements of proto-TRK and proto-RET genes, display a constitutive phosphorylation on tyrosine. Tyrosine ret proto-oncogene Homo sapiens
2 Chimeric Ret and Trk oncoproteins, encoded by different rearrangements of proto-TRK and proto-RET genes, display a constitutive phosphorylation on tyrosine. Tyrosine ret proto-oncogene Homo sapiens
3 In addition, in cells containing either Ret or Trk oncoproteins, Shc proteins are constitutively phosphorylated on tyrosine and bound to Grb2. Tyrosine ret proto-oncogene Homo sapiens