Title : Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter.

Pub. Date : 1994 Apr 8

PMID : 8144600






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In hepatocytes, fructose in low concentrations is phosphorylated into fructose 1-phosphate, and therefore is able to active GK in the absence of insulin via the regulatory protein in the liver. Fructose glucokinase Rattus norvegicus
2 In the presence of glucose, the L-PK promoter can also be activated by a post-translational GK activation, mediated by a low concentration of fructose acting via the regulatory protein of glucokinase. Fructose glucokinase Rattus norvegicus
3 In the presence of glucose, the L-PK promoter can also be activated by a post-translational GK activation, mediated by a low concentration of fructose acting via the regulatory protein of glucokinase. Fructose glucokinase Rattus norvegicus