Protein Name glucokinase
Organism Rattus norvegicus
Gene ID 24385
Gene Symbol

Gck

UniProt P17712 (HXK4_RAT), X2G6B3 (X2G6B3_RAT), Q64596 (Q64596_RAT)
Relationships Total Number of functionally related compound(s) : 297
Total Number of Articles : 472
Description

glucokinase

Gene Summary

Enables several functions, including D-glucose binding activity; adenyl ribonucleotide binding activity; and hexokinase activity. Involved in several processes, including hexose metabolic process; positive regulation of phosphate metabolic process; and regulation of secretion by cell. Located in several cellular components, including actin filament; basal cortex; and secretory granule. Used to study obesity; steatotic liver disease; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in artery disease (multiple) and glucose metabolism disease (multiple). Orthologous to human GCK (glucokinase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • hexokinase-4
  • HK IV
  • HK4
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Properties