Protein Name glucokinase
Organism Rattus norvegicus
Gene ID 24385
Gene Symbol


UniProt P17712 (HXK4_RAT), X2G6B3 (X2G6B3_RAT), Q64596 (Q64596_RAT)
Relationships Total Number of functionally related compound(s) : 297
Total Number of Articles : 472


Gene Summary

Enables several functions, including adenyl ribonucleotide binding activity; glucose binding activity; and hexokinase activity. Involved in several processes, including cellular chemical homeostasis; cellular response to hormone stimulus; and hexose metabolic process. Located in several cellular components, including basal cortex; nucleoplasm; and secretory granule. Colocalizes with actin filament. Used to study fatty liver disease; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in artery disease (multiple); familial hyperinsulinemic hypoglycemia 3; and glucose metabolism disease (multiple). Orthologous to human GCK (glucokinase). [provided by Alliance of Genome Resources, Apr 2022]

  • hexokinase-4
  • HK IV
  • HK4
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