Pub. Date : 1994 Feb
PMID : 8134404
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effects of anti-TNF-alpha antibody and dexamethasone on TCDD-induced oxidative stress in mice. | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 2 | Recent studies have implicated tumor necrosis factor alpha (TNF-alpha) in the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 3 | Recent studies have implicated tumor necrosis factor alpha (TNF-alpha) in the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 4 | Recent studies have implicated tumor necrosis factor alpha (TNF-alpha) in the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 5 | Recent studies have implicated tumor necrosis factor alpha (TNF-alpha) in the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 6 | Since TNF-alpha sensitizes and activates phagocytic cells to agents that induce them to release reactive oxygen species, TNF-alpha may act as an amplifying loop in TCDD-induced oxidative stress (OS). | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 7 | Since TNF-alpha sensitizes and activates phagocytic cells to agents that induce them to release reactive oxygen species, TNF-alpha may act as an amplifying loop in TCDD-induced oxidative stress (OS). | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 8 | One day after treatment with 125 micrograms TCDD/kg, anti-TNF-alpha resulted in 70, 27, 33 and 21% decreases in DNA-SSB, mitochondrial and microsomal lipid peroxidation and PLC activation, respectively, relative to TCDD-treated mice. | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 9 | One day after treatment with 125 micrograms TCDD/kg, anti-TNF-alpha resulted in 70, 27, 33 and 21% decreases in DNA-SSB, mitochondrial and microsomal lipid peroxidation and PLC activation, respectively, relative to TCDD-treated mice. | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 10 | The results suggest that TNF-alpha release may play a role in sensitizing and activating phagocytic cells following treatment with TCDD, contributing to the overall OS of animals following exposure to TCDD. | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |
| 11 | The results suggest that TNF-alpha release may play a role in sensitizing and activating phagocytic cells following treatment with TCDD, contributing to the overall OS of animals following exposure to TCDD. | Polychlorinated Dibenzodioxins | tumor necrosis factor | Mus musculus |