Title : Activation of mitogen activated protein (MAP) kinases by vanadate is independent of insulin receptor autophosphorylation.

Pub. Date : 1994 Mar 7

PMID : 8131857






1 Functional Relationships(s)
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1 Treatment of Chinese hamster ovary (CHO) cells over-expressing the human insulin receptor (CHO-HIRc) with the insulin mimetic agent, vanadate, resulted in a dose- and time-dependent tyrosine phosphorylation of two proteins with apparent molecular sizes of 42 kDa (p42) and 44 kDa (p44). Vanadates insulin receptor Homo sapiens