Title : Thermoregulation with age: role of thermogenesis and uncoupling protein expression in brown adipose tissue.

Pub. Date : 1994 Feb

PMID : 8108465






3 Functional Relationships(s)
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1 To this end, we assessed body temperature, guanosine 5"-diphosphate (GDP) binding to the IBAT mitochondrial uncoupling protein (UCP) and the induction of UCP mRNA after both 1-hr and 48-hr mild cold exposures at 8 degrees C and after a more severe, 1-hr cold exposure at 4 degrees C in 3- and 24-month-old F-344 rats. Guanosine Diphosphate uncoupling protein 1 Rattus norvegicus
2 To this end, we assessed body temperature, guanosine 5"-diphosphate (GDP) binding to the IBAT mitochondrial uncoupling protein (UCP) and the induction of UCP mRNA after both 1-hr and 48-hr mild cold exposures at 8 degrees C and after a more severe, 1-hr cold exposure at 4 degrees C in 3- and 24-month-old F-344 rats. Guanosine Diphosphate uncoupling protein 1 Rattus norvegicus
3 GDP binding to UCP increased 75% following cold exposure and, surprisingly was the same in young and old rats. Guanosine Diphosphate uncoupling protein 1 Rattus norvegicus