Protein Name uncoupling protein 1
Organism Rattus norvegicus
Gene ID 24860
Gene Symbol


UniProt P04633 (UCP1_RAT)
Relationships Total Number of functionally related compound(s) : 182
Total Number of Articles : 222

uncoupling protein 1

Gene Summary

Enables GDP binding activity; GTP binding activity; and oxidative phosphorylation uncoupler activity. Involved in several processes, including cellular response to hormone stimulus; cellular response to lipid; and proton transmembrane transport. Located in mitochondrion. Biomarker of prediabetes syndrome. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1). [provided by Alliance of Genome Resources, Apr 2022]

  • mitochondrial brown fat uncoupling protein 1
  • UCP 1
  • mitochondrial brown fat uncoupling protein 1-like
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