Pub. Date : 1993 Jan
PMID : 8093438
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Estradiol is selectively neurotoxic to hypothalamic beta-endorphin neurons. | Estradiol | proopiomelanocortin | Homo sapiens |
2 | Eight weeks after EV treatment, a 60% decrease in the total number of beta-endorphin-immunoreactive neurons was detected in the arcuate nucleus. | Estradiol | proopiomelanocortin | Homo sapiens |
3 | The evidence indicates that the selective neurotoxic effect of estradiol on hypothalamic beta-endorphin neurons contributes to reproductive senescence, suggesting that steroids may participate in disruption of the biological functions that they normally facilitate. | Estradiol | proopiomelanocortin | Homo sapiens |