Title : Estradiol is selectively neurotoxic to hypothalamic beta-endorphin neurons.

Pub. Date : 1993 Jan

PMID : 8093438






3 Functional Relationships(s)
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1 Estradiol is selectively neurotoxic to hypothalamic beta-endorphin neurons. Estradiol proopiomelanocortin Homo sapiens
2 Eight weeks after EV treatment, a 60% decrease in the total number of beta-endorphin-immunoreactive neurons was detected in the arcuate nucleus. Estradiol proopiomelanocortin Homo sapiens
3 The evidence indicates that the selective neurotoxic effect of estradiol on hypothalamic beta-endorphin neurons contributes to reproductive senescence, suggesting that steroids may participate in disruption of the biological functions that they normally facilitate. Estradiol proopiomelanocortin Homo sapiens