Title : Leu 193 mutation in the cysteine rich region of the insulin receptor inhibits the cleavage of the insulin receptor precursor but not insulin binding.

Pub. Date : 1994 Sep 15

PMID : 8093054






3 Functional Relationships(s)
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1 Leu 193 mutation in the cysteine rich region of the insulin receptor inhibits the cleavage of the insulin receptor precursor but not insulin binding. Leucine insulin receptor Homo sapiens
2 Leu 193 mutation in the cysteine rich region of the insulin receptor inhibits the cleavage of the insulin receptor precursor but not insulin binding. Leucine insulin receptor Homo sapiens
3 To characterize the Leu 193 mutant insulin receptor, which was found in a patient with extreme insulin resistance, the mutant insulin receptor was overexpressed in Rat-1 fibroblasts by transfection of mutated insulin receptor cDNA. Leucine insulin receptor Homo sapiens