Title : D2 dopamine receptor gene and cigarette smoking: a reward gene?

Pub. Date : 1994 Apr

PMID : 8072432






1 Functional Relationships(s)
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1 In as much as alcohol, cocaine, opiates, nicotine and food are known to increase brain dopamine levels and activate the mesocorticolimbic dopaminergic reward pathways of the brain, it is hypothesized that an inherited deficit of D2 dopamine receptor numbers in brain reward areas of A1 allelic subject predisposes them to substance abuse problems. Nicotine dopamine receptor D2 Homo sapiens