Title : Expression of interleukin 1 alpha, interleukin 6, and tumor necrosis factor alpha genes in human melanoma clones is associated with that of mutated N-RAS oncogene.

Pub. Date : 1994 Sep 1

PMID : 8062279






1 Functional Relationships(s)
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1 Five of these clones and the parental cell line showed a mutation at codon 61 of N-RAS that resulted in Gln-->Arg substitution (N-RAS/61+), while in the remaining 14, only the wild-type allele for N-RAS was present (N-RAS/61-). Arginine NRAS proto-oncogene, GTPase Homo sapiens