Title : Topical glucocorticosteroids modulate the expression of CRABP I and II in human skin differently.

Pub. Date : 1994 Feb

PMID : 8061932






2 Functional Relationships(s)
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1 We found that CRABP II protein and mRNA were strongly increased upon retinoic acid application: this induction was significantly inhibited by concomitant application of triamcinolone acetonide; a more potent steroid, difluocortolone valerate, was also found to diminish normal endogenous expression of CRABP II. Triamcinolone Acetonide cellular retinoic acid binding protein 2 Homo sapiens
2 We found that CRABP II protein and mRNA were strongly increased upon retinoic acid application: this induction was significantly inhibited by concomitant application of triamcinolone acetonide; a more potent steroid, difluocortolone valerate, was also found to diminish normal endogenous expression of CRABP II. Triamcinolone Acetonide cellular retinoic acid binding protein 2 Homo sapiens