Pub. Date : 1994 Apr
PMID : 8045845
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine and acetylcholine induce release of calcitonin gene-related peptide from rat trachea. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 2 | In the present study, we observed that nicotine, the nicotinic analogue cytisine, and acetylcholine (ACh) evoked a concentration-dependent (5 x 10(-6)-5 x 10(-5) M) release of calcitonin gene-related peptide (CGRP) from the rat trachea. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 3 | In the present study, we observed that nicotine, the nicotinic analogue cytisine, and acetylcholine (ACh) evoked a concentration-dependent (5 x 10(-6)-5 x 10(-5) M) release of calcitonin gene-related peptide (CGRP) from the rat trachea. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 4 | In the present study, we observed that nicotine, the nicotinic analogue cytisine, and acetylcholine (ACh) evoked a concentration-dependent (5 x 10(-6)-5 x 10(-5) M) release of calcitonin gene-related peptide (CGRP) from the rat trachea. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 5 | In the present study, we observed that nicotine, the nicotinic analogue cytisine, and acetylcholine (ACh) evoked a concentration-dependent (5 x 10(-6)-5 x 10(-5) M) release of calcitonin gene-related peptide (CGRP) from the rat trachea. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 6 | Hexamethonium and mecamylamine blocked the effect of nicotine but not that of ACh, whereas atropine significantly attenuated the release of CGRP outflow induced by ACh. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 7 | Physostigmine and neostigmine did not alter resting release of CGRP from rat trachea, although exogenous (10(-5) M) ACh-induced CGRP release was enhanced in the presence of neostigmine, suggesting minimal tonic cholinergic activity in this model. | Acetylcholine | calcitonin-related polypeptide alpha | Rattus norvegicus |