Title : Thymidylate synthase activity, folates, and glutathione system in head and neck carcinoma and adjacent tissues.

Pub. Date : 1994 Mar-Apr

PMID : 8021136






1 Functional Relationships(s)
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1 Because the glutathione (GSH) system and thymidylate synthase (TS) are involved in the resistance to the main drugs used in HNSCC (cisplatin and 5-FU), we studied these systems in tumors and normal mucosae. Cisplatin thymidylate synthetase Homo sapiens