Pub. Date : 1994 Mar-Apr
PMID : 8014029
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased interleukin 2 transcription in murine lymphocytes by ciprofloxacin. | Ciprofloxacin | interleukin 2 | Mus musculus |
| 2 | In this investigation an enhanced and prolonged IL-2 and IL-2 mRNA response was also detected in both stimulated (T cell mitogens or alloantigens) murine splenocytes and in the stimulated murine T cell line EL-4 in the presence of ciprofloxacin (5-80 micrograms/ml) as compared to control cells without antibiotics. | Ciprofloxacin | interleukin 2 | Mus musculus |
| 3 | In this investigation an enhanced and prolonged IL-2 and IL-2 mRNA response was also detected in both stimulated (T cell mitogens or alloantigens) murine splenocytes and in the stimulated murine T cell line EL-4 in the presence of ciprofloxacin (5-80 micrograms/ml) as compared to control cells without antibiotics. | Ciprofloxacin | interleukin 2 | Mus musculus |
| 4 | Analysis of CAT activity revealed that cipro enhanced IL-2 gene induction. | Ciprofloxacin | interleukin 2 | Mus musculus |
| 5 | Taken together, cipro inhibited IFN-gamma synthesis, but enhanced IL-2 production in murine lymphocytes by means of influencing NFAT-1 and causing an increased IL-2 transcription. | Ciprofloxacin | interleukin 2 | Mus musculus |
| 6 | Taken together, cipro inhibited IFN-gamma synthesis, but enhanced IL-2 production in murine lymphocytes by means of influencing NFAT-1 and causing an increased IL-2 transcription. | Ciprofloxacin | interleukin 2 | Mus musculus |