Protein Name cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
Organism Rattus norvegicus
Gene ID 25642
Gene Symbol

Cyp3a23-3a1

UniProt Q06884 (Q06884_RAT)
Relationships Total Number of functionally related compound(s) : 615
Total Number of Articles : 567
Description

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

Gene Summary

Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in several processes, including oxidative demethylation; response to cadmium ion; and response to dexamethasone. Located in endoplasmic reticulum membrane. Biomarker of cholestasis and mental depression. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytochrome P450 3A1
  • CYPIIIA1
  • Cytochrome P450, subfamily IIIA, polypeptide 3
Click to show/hide the synonyms
Properties