Protein Name | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
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Organism | Rattus norvegicus |
Gene ID | 25642 |
Gene Symbol | Cyp3a23-3a1 |
UniProt | Q06884 (Q06884_RAT) |
Relationships |
Total Number of functionally related compound(s) :
615
Total Number of Articles : 567 |
Description |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
Gene Summary |
Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in several processes, including oxidative demethylation; response to cadmium ion; and response to dexamethasone. Located in endoplasmic reticulum membrane. Biomarker of cholestasis and mental depression. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022] |
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