Title : Acute inflammatory injury in the lung precipitated by oxidant stress induces fibroblasts to synthesize and release transforming growth factor-alpha.

Pub. Date : 1994 Oct 7

PMID : 7929192






1 Functional Relationships(s)
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1 Conditioned media from these fibroblasts stimulated tyrosine phosphorylation of the epidermal growth factor (EGF)/TGF-alpha receptor, competed with radioactive EGF for binding sites on A431 cells, and were mitogenic for mesenchymal and epithelial cells. Tyrosine transforming growth factor alpha Homo sapiens