Pub. Date : 1993 Jun
PMID : 7920881
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TSH secretory responses to prolonged infusion of TRH in hypothyroid rats. | Thyrotropin | thyrotropin releasing hormone | Rattus norvegicus |
| 2 | Infusion of a constant concentration of TRH induced a peak in the plasma TSH concentration within 5-15 min which declined to the baseline within 1 h. The refractory period lasted 20-40 min after stopping the continuous TRH infusion. | Thyrotropin | thyrotropin releasing hormone | Rattus norvegicus |
| 3 | A second burst of TSH secretion was induced by increasing the TRH concentration during the refractory period while TRH was being continuously infused. | Thyrotropin | thyrotropin releasing hormone | Rattus norvegicus |
| 4 | A second burst of TSH secretion was induced by increasing the TRH concentration during the refractory period while TRH was being continuously infused. | Thyrotropin | thyrotropin releasing hormone | Rattus norvegicus |
| 5 | These data indicate that in hypothyroid rats TSH secretion rapidly becomes refractory to continuous exposure to the same concentration of TRH but is stimulated by a higher TRH concentration. | Thyrotropin | thyrotropin releasing hormone | Rattus norvegicus |
| 6 | These data indicate that in hypothyroid rats TSH secretion rapidly becomes refractory to continuous exposure to the same concentration of TRH but is stimulated by a higher TRH concentration. | Thyrotropin | thyrotropin releasing hormone | Rattus norvegicus |