Pub. Date : 1994 May
PMID : 7915013
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tetrahydrobiopterin (BH4), the obligatory cofactor of the aromatic amino acid hydroxylases, decreased the in situ 32P-phosphorylation of tyrosine hydroxylase (TH) in rat striatal synaptosomes. | Phosphorus-32 | tyrosine hydroxylase | Rattus norvegicus |
| 2 | Tetrahydrobiopterin (BH4), the obligatory cofactor of the aromatic amino acid hydroxylases, decreased the in situ 32P-phosphorylation of tyrosine hydroxylase (TH) in rat striatal synaptosomes. | Phosphorus-32 | tyrosine hydroxylase | Rattus norvegicus |
| 3 | Incubation of pre-32P-labeled synaptosomes with BH4 in the presence of a permeant analogue of cAMP decreased the cAMP-stimulated level of 32P label incorporation into TH by about 50%, as determined by immunoprecipitation and autoradiography of SDS-polyacrylamide gels. | Phosphorus-32 | tyrosine hydroxylase | Rattus norvegicus |
| 4 | Incubation of pre-32P-labeled synaptosomes with BH4 in the presence of a permeant analogue of cAMP decreased the cAMP-stimulated level of 32P label incorporation into TH by about 50%, as determined by immunoprecipitation and autoradiography of SDS-polyacrylamide gels. | Phosphorus-32 | tyrosine hydroxylase | Rattus norvegicus |
| 5 | A similar decrease in the amount of TH 32P-labeling was observed with the precursor of BH4, sepiapterin. | Phosphorus-32 | tyrosine hydroxylase | Rattus norvegicus |