Title : 2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo.

Pub. Date : 1993 Oct

PMID : 7905506






1 Functional Relationships(s)
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1 The autophosphorylation of interferon (IFN)-induced double-stranded RNA-dependent p68 protein kinase (PKR) and phosphorylation of the alpha-subunit of the translation initiation factor eIF-2 were inhibited by 10 mM 2-aminopurine in vitro. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens