Pub. Date : 1993 Oct
PMID : 7902969
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A single nicotine injection resulted in a rapid and transient activation phase of nerve growth factor I-A, c-fos and jun-B at 20 min, and a later and less prominent activation of c-jun, which stayed high from 20 to 60 min. | Nicotine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | When repeated nicotine injections were given, there was a refractory period of 1-2 h for c-fos, nerve growth factor I-A and jun-B induction. | Nicotine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Repeated nicotine injections at 1-h intervals prevented about 80% of c-fos, nerve growth factor I-A and jun-B mRNA induction seen after a single injection. | Nicotine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |