Title : Nicotine increases expression of tyrosine hydroxylase gene. Involvement of protein kinase A-mediated pathway.

Pub. Date : 1993 Nov 5

PMID : 7901211






1 Functional Relationships(s)
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1 Nicotine, a major component of tobacco smoke, stimulates catecholamine secretion and activates catecholamine biosynthetic enzymes such as tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) in adrenal medullary cells. Catecholamines dopamine beta-hydroxylase Rattus norvegicus