Title : Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26-derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10.

Pub. Date : 1995 Apr 1

PMID : 7897221






2 Functional Relationships(s)
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1 Colon-26-derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10. Dinoprostone interleukin 10 Mus musculus
2 Taken together, these results support the hypothesis that tumor-derived PGE2 prevents tumor-infiltrating macrophages from producing TNF-alpha, in part by augmenting macrophage IL-10 synthesis. Dinoprostone interleukin 10 Mus musculus