Title : Anomalous effects of losartan on aminopeptidase-induced reductions of blood pressure in SHR.

Pub. Date : 1995

PMID : 7895095






1 Functional Relationships(s)
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1 Pretreatment with the angiotensin II (AngII) receptor subtype 1 (AT1) antagonist, DuP 753 (losartan) significantly attenuated this hypotensive effect, in a dose-dependent manner, while pretreatment with the AngII receptor subtype 2 (AT2) antagonist, PD123177, did not influence AmM-induced hypotension. PD 123177 angiotensin II receptor, type 1a Rattus norvegicus