Title : Mechanistic study of the inhibition of aflatoxin b1-induced hepatotoxicity by dimethyl 4,4'-dimethoxy-5,6,5',6'-dimethylenedioxy biphenyl-2, 2'-dicarboxylate.

Pub. Date : 1995 Mar 2

PMID : 7889530






1 Functional Relationships(s)
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1 It is concluded that the protective effect of DDB against AFB1-induced damage might be mediated by the induced glutathione S-transferase activity and not from the accelerated hepatic cytochrome P450 detoxification pathway of AFB1 which was previously believed. Aflatoxin B1 hematopoietic prostaglandin D synthase Rattus norvegicus