Pub. Date : 1995 Feb 28
PMID : 7877973
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PDGF-induced transcription, translation, and secretion of IL-6 were diminished in the presence of IL-6 antisense oligonucleotides. | Oligonucleotides | interleukin 6 | Homo sapiens |
| 2 | PDGF-induced transcription, translation, and secretion of IL-6 were diminished in the presence of IL-6 antisense oligonucleotides. | Oligonucleotides | interleukin 6 | Homo sapiens |
| 3 | While neutralizing anti-IL-6 antibodies failed to affect the growth factor-dependent cell proliferation, IL-6 antisense oligonucleotides inhibited cell division. | Oligonucleotides | interleukin 6 | Homo sapiens |
| 4 | In addition, IL-6 antisense oligonucleotides abolished PDGF-induced transcription of the genes coding for the cell division cycle 2-related protein (CDC2) and proliferating cell nuclear antigen (PCNA), both of which are regulated in a cell cycle-dependent manner. | Oligonucleotides | interleukin 6 | Homo sapiens |