Title : NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea.

Pub. Date : 1995 Feb

PMID : 7864147






1 Functional Relationships(s)
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1 Pretreatment with the NK1 receptor antagonist CP-96,345 (4 mg/kg iv), before challenge with substance P, capsaicin, or aerosol hypertonic saline, reduced the amount of neutrophil adhesion by 56%, 93%, and 57% and reduced the amount of eosinophil adhesion by 70%, 83%, and 65%, respectively. CP96 tachykinin receptor 1 Rattus norvegicus