Protein Name tachykinin receptor 1
Organism Rattus norvegicus
Gene ID 24807
Gene Symbol

Tacr1

UniProt P14600 (NK1R_RAT)
Relationships Total Number of functionally related compound(s) : 405
Total Number of Articles : 552
Description

tachykinin receptor 1

Gene Summary

Enables substance P receptor activity. Involved in several processes, including learning or memory; positive regulation of secretion; and regulation of cell migration. Located in several cellular components, including cell body; cell surface; and dendrite. Used to study central sleep apnea; cystitis; pancreatitis; and pulmonary hypertension. Biomarker of acute necrotizing pancreatitis; allergic rhinitis; asthma; colitis; and respiratory syncytial virus infectious disease. Human ortholog(s) of this gene implicated in exercise-induced bronchoconstriction. Orthologous to human TACR1 (tachykinin receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • substance-P receptor
  • NK-1 receptor
  • NK-1R
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Properties