Pub. Date : 1994 Nov
PMID : 7855736
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Amphetamine- and cocaine-induced fos in the rat striatum depends on D2 dopamine receptor activation. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Amphetamine or cocaine injection causes expression of the immediate-early gene c-fos in the striatum. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Eticlopride treatment (0.5 mg/kg) caused Fos expression by itself, but also decreased Fos expression in the central striatum due to amphetamine (5.0 mg/kg) or cocaine (40 mg/kg) by 90% and 85%, respectively. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | In striatonigral neurons, identified by labeling with the retrograde tracer Fluorogold iontophoresed into the substantia nigra pars reticulata, the blockade of stimulant-induced Fos-like immunofluorescence by eticlopride was nearly complete, with decreases of 98% for amphetamine and 94% for cocaine. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |