Title : Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid.

Pub. Date : 1994 Oct

PMID : 7854071






1 Functional Relationships(s)
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1 Pretreatment with the non-competitive NMDA antagonist MK-801 (2 mg/kg, 30 min before the insult), partially blocked the increase in both BDNF and NGF mRNAs, as well as the decrease in NT3, in the contralateral hippocampus. N-Methylaspartate brain-derived neurotrophic factor Rattus norvegicus