Title : Effect of estradiol and progesterone on cholesterol 7 alpha-hydroxylase activity in rats subjected to different feeding conditions.

Pub. Date : 1994 Sep

PMID : 7846735






2 Functional Relationships(s)
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1 The regulation of cholesterol 7 alpha-hydroxylase activity by estradiol and progesterone was investigated in liver microsomes isolated from rats fed standard diet, either ad libitum or fasted for 24 h, and diet containing the bile acid sequesterant cholestyramine. Cholestyramine Resin cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus
2 The administration of estradiol (50 micrograms) or progesterone (100 micrograms) for 21 days resulted in depressed cholesterol 7 alpha-hydroxylase activity in rats with high bile acid synthesis basal rate due to cholestyramine feeding. Cholestyramine Resin cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus